The polysomnogram continuously records brain waves during sleep, as well as a number of nerve and muscle functions during nighttime sleep. Stanford Sleep Specialists use two main tests to diagnose narcolepsy: the nocturnal polysomnogram and the multiple sleep latency test (MSLT). A general medical check up excluding anemia, hypothyroidism, heart or other general medical issues is essential. It requires excluding carefully insufficient sleep (sleep deprivation), disturbed nocturnal sleep, insomnia, circadian rhythm disorders, sleep-related breathing (sleep apnea) disorders and psychiatric disorders. However, if sleep attacks are isolated and there is only mild or no cataplexy, making a correct diagnosis is more challenging. If all the common symptoms of narcolepsy are present, diagnosing the disorder is fairly straightforward. In most cases of narcolepsy without cataplexy (and in rare cases with cataplexy), the cause of the symptoms is unclear and the diagnostic is purely based on the result of an abnormal sleep test called the multiple sleep latency test (MSLT). Visit the Center for Narcolepsy for more details. In most cases of narcolepsy with cataplexy (and in rare cases without cataplexy), all the symptoms are caused by the loss of approximately 70,000 brain cells producing a chemical called hypocretin, a finding made at Stanford University. The cause of narcolepsy with and without cataplexy Obesity – Many patients with narcolepsy also gain weight as the result of inactivity and sleepiness.

Nighttime eating and excessive dreaming with motor activity (acting out dreams, see also REM sleep Behavior Disorder) also frequently occur. Patients often do fall asleep rapidly but are unable to stay asleep for more than a few hours at a time.

Hypnagogic hallucinations – vivid, sometimes disturbing dreamlike experiences that occur while dozing, falling asleep and/or upon awakening.Īutomatic behavior – a person continues to function or talk while being half asleep, and awakens with no memory of doing these activities.ĭifficulties maintaining sleep – Nighttime sleep is disturbed. Sleep paralysis - the temporary inability to talk or move when waking it may last a few seconds to minutes. Cataplexy is a cardinal symptom as it almost always indicates that the cause of the narcolepsy is a lack of hypocretin in the brain. While cataplexy can manifest as something as minor as a slight slackening of the facial muscles, in extreme cases, a person may experience total collapse or even muscle paralysis. Beside excessive daytime sleepiness, patients may display the following symptoms:Ĭataplexy – a sudden weakening of the muscles, often triggered by a strong emotion.

Narcolepsy without cataplexy